Discovery of a Potent, Selective, and Orally Active Proteasome Inhibitor for the Treatment of Cancer
Author:
Affiliation:
1. Cephalon, Inc., 145 Brandywine Parkway, West Chester, Pennsylvania 19380, and Cell Therapeutics Europe S.r.l., Via L. Ariosto, 23, I-20091 Bresso, Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm7010589
Reference28 articles.
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4. The catalytic sites of 20S proteasomes and their role in subunit maturation: A mutational and crystallographic study
5. Proteasome Inhibitors as Therapeutic Agents: Current and Future Strategies
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