Fragment-Based Discovery of New Highly Substituted 1H-Pyrrolo[2,3-b]- and 3H-Imidazolo[4,5-b]-Pyridines as Focal Adhesion Kinase Inhibitors-Reference-Cited by-同舟云学术

Fragment-Based Discovery of New Highly Substituted 1H-Pyrrolo[2,3-b]- and 3H-Imidazolo[4,5-b]-Pyridines as Focal Adhesion Kinase Inhibitors

Published:2013-01-22 Issue:3 Volume:56 Page:1160-1170
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Heinrich Timo¹,Seenisamy Jeyaprakashnarayanan²,Emmanuvel Lourdusamy³,Kulkarni Santosh S.²,Bomke Jörg¹,Rohdich Felix¹,Greiner Hartmut¹,Esdar Christina¹,Krier Mireille¹,Grädler Ulrich¹,Musil Djordje¹

Affiliation:

1. Merck Serono Research, Merck KGaA, 64271 Darmstadt, Germany

2. Syngene International Ltd., Biocon Park, Plot 2&3, Bommasandra-Jigani Link Road, Bangalore 560 099, India

3. Department of Chemistry, School of Science and Humanities, Karunya University, Coimbatore 641114, India

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3016014

Reference51 articles.

1. Focal Adhesion Kinase

2. Focal Adhesion Kinase: From In Vitro Studies to Functional Analyses In Vivo

3. Multiple connections link FAK to cell motility and invasion

4. Organization and post-transcriptional processing of focal adhesion kinase gene

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