2-[(2-Aminobenzyl)sulfinyl]-1-(2-pyridyl)-1,4,5,6-tetrahydrocyclopent[d]imidazoles as a Novel Class of Gastric H+/K+-ATPase Inhibitors-Reference-Cited by-同舟云学术

2-[(2-Aminobenzyl)sulfinyl]-1-(2-pyridyl)-1,4,5,6-tetrahydrocyclopent[d]imidazoles as a Novel Class of Gastric H+/K+-ATPase Inhibitors

Published:1996-01-01 Issue:2 Volume:39 Page:596-604
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yamada Masaki¹,Yura Takeshi¹,Morimoto Masamichi¹,Harada Tsunehiro¹,Yamada Koichiro¹,Honma Yasushi¹,Kinoshita Mine¹,Sugiura Masaki¹

Affiliation:

1. Organic Chemistry Research Laboratory, Biological Research Laboratory, and Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co., Ltd., 2-2-50 Kawagishi, Toda-shi, Saitama 335, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm950610n

Reference36 articles.

1. Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+) ATPase

2. The mechanism of action of the antisecretory agent omeprazole

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