2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with Selective Affinity for the 5-HT4 Receptor: Synthesis and Structure−Affinity and Structure−Activity Relationships of a New Series of Partial Agonist and Antagonist Derivatives-Reference-Cited by-同舟云学术

2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with Selective Affinity for the 5-HT4 Receptor: Synthesis and Structure−Affinity and Structure−Activity Relationships of a New Series of Partial Agonist and Antagonist Derivatives

Published:1999-07-01 Issue:15 Volume:42 Page:2870-2880
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tapia Inés¹,Alonso-Cires Luisa¹,López-Tudanca Pedro Luis¹,Mosquera Ramón¹,Labeaga Luis¹,Innerárity Ana¹,Orjales Aurelio¹

Affiliation:

1. Departamento de Investigación, FAES, S.A., Máximo Aguirre 14, 48940 Leioa, Vizcaya, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm981098j

Reference37 articles.

1. The gastrointestinal prokinetic benzamide derivatives are agonists at the non-classical 5-HT receptor (5-HT4) positively coupled to adenylate cyclase in neurons

2. Central 5-HT4 receptors

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