High-Throughput Catch-and-Release Synthesis of Oxazoline Hydroxamates. Structure−Activity Relationships in Novel Inhibitors of Escherichia coli LpxC: In Vitro Enzyme Inhibition and Antibacterial Properties
Author:
Affiliation:
1. Contribution from the Department of Chemistry, Levine Science Research Center, Box 90317, Duke University, Durham, North Carolina 27708-0317, and Department of Biochemistry, Box 3711, Duke University Medical Center, Durham, North Carolina 27710
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja0209114
Reference20 articles.
1. Resisting resistance: new chemical strategies for battling superbugs
2. An Antibiotic Cloaked by Its Own Resistance Enzyme
3. Funding Crunch Hobbles Antibiotic Resistance Research
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