Mechanism of RNA 2‘-O-Methylation: Evidence that the Catalytic Lysine Acts To Steer Rather than Deprotonate the Target Nucleophile-Reference-Cited by-同舟云学术

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Mechanism of RNA 2‘-O-Methylation: Evidence that the Catalytic Lysine Acts To Steer Rather than Deprotonate the Target Nucleophile

Published:2004-04-23 Issue:19 Volume:43 Page:5680-5687
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Li C.¹,Xia Y.¹,Gao X.¹,Gershon P. D.¹

Affiliation:

1. Department of Medical Biochemistry and Genetics/Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Houston, Texas 77030, and Department of Chemistry, University of Houston, 136 Fleming Street, Houston, Texas 77204-5003

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi0359980

Reference53 articles.

1. S-Adenosylmethionine-Dependent Methyltransferases

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2. Enzymatic Assays to Explore Viral mRNA Capping Machinery;ChemBioChem;2021-08-03

3. Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2′- O -methyl transfer by SARS-CoV-2 nsp16;Science Signaling;2021-06-29

4. Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2′-O-methyl transfer by SARS-CoV-2 nsp16;2021-02-01

5. Functional and computational identification of a rescue mutation near the active site of an mRNA methyltransferase;Scientific Reports;2020-12

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