Nonenzymatic, Template-Directed Ligation of Oligoribonucleotides Is Highly Regioselective for the Formation of 3‘−5‘ Phosphodiester Bonds
Author:
Affiliation:
1. Contribution from the Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja9537134
Reference23 articles.
1. Joyce, G. F.; Orgel, L. E. InThe RNA World; Gesteland, R. F., Atkins, J. F., Eds.; Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, 1993; pp 1−25.
2. RNA catalysis and the origins of life
3. Preferential formation of (2'–5')-linked internucleotide bonds in non-enzymatic reactions
4. Heteropolynucleotides as templates for non-enzymatic polymerizations
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