Behavioral Approach to Nondyskinetic Dopamine Antagonists: Identification of Seroquel-Reference-Cited by-同舟云学术

Behavioral Approach to Nondyskinetic Dopamine Antagonists: Identification of Seroquel

Published:2001-01-03 Issue:3 Volume:44 Page:372-389
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Warawa Edward J.¹,Migler Bernard M.¹,Ohnmacht Cyrus J.¹,Needles Ann L.¹,Gatos George C.¹,McLaren Frances M.¹,Nelson Cynthia L.¹,Kirkland Karen M.¹

Affiliation:

1. Departments of Medicinal Chemistry, Pharmacology, and Drug Disposition and Metabolism, AstraZeneca Pharmaceuticals LP, P.O. Box 15437, Wilmington, Delaware 19850-5437

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000242%2B

Reference47 articles.

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2. Clozapine for the Treatment-Resistant Schizophrenic

3. CLOZAPINE AND AGRANULOCYTOSIS

4. “The apomorphine gnawing test- - -was not available at that time. This was perhaps fortunate, since lack of activity of clozapine in that test might have stopped its further development” (p 41). Schmutz, J.; Eichenberger, E. Clozapine. InChronicles of Drug Discovery;Bindra, J. S., Lednicer, D., Eds.; John Wiley & Sons: New York, 1982; Vol. 1, pp 39−59.

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