Validation of Model of Cytochrome P450 2D6: An in Silico Tool for Predicting Metabolism and Inhibition-Reference-Cited by-同舟云学术

Validation of Model of Cytochrome P450 2D6: An in Silico Tool for Predicting Metabolism and Inhibition

Published:2004-09-21 Issue:22 Volume:47 Page:5340-5346
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kemp Carol A.¹,Flanagan Jack U.¹,van Eldik Annamaria J.¹,Maréchal Jean-Didier¹,Wolf C. Roland¹,Roberts Gordon C. K.¹,Paine Mark J. I.¹,Sutcliffe Michael J.¹

Affiliation:

1. Departments of Biochemistry and Chemistry, University of Leicester, University Road, Leicester, LE1 7RH, U.K., Biomedical Research Centre, University of Dundee, Ninewells Hospital & Medical School, Dundee, DD1 9SY, U.K., and Biological NMR Centre and Department of Biochemistry, University of Leicester, P.O. Box 138, Leicester, LE1 9HN, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049934e

Reference31 articles.

1. Metabolism of36Cl-ornidazole after oral application to the male rat in relation to its antifertility activity

2. Recent Advances: the Cytochrome P450 Enzymes

3. Inhibition of Risperidone Metabolism by Fluoxetine in Patients With Schizophrenia: A Clinically Relevant Pharmacokinetic Drug Interaction

Cited by 77 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Investigation of in silico studies for cytochrome P450 isoforms specificity;Computational and Structural Biotechnology Journal;2024-12

2. Development of Parenting Models, Infrastructure and Management Health in Management of Day Care for Melati State University of Malang;Proceedings of the International Conference on Educational Management and Technology (ICEMT 2022);2023

3. “Commandeuring” Xenobiotic Metabolism: Advances in Understanding Xenobiotic Metabolism;Chemical Research in Toxicology;2022-06-29

4. Computational approaches for drug-metabolizing enzymes: Concepts and challenges;Biochemistry of Drug Metabolizing Enzymes;2022

5. Descriptors of Cytochrome Inhibitors and Useful Machine Learning Based Methods for the Design of Safer Drugs;Pharmaceuticals;2021-05-17