Enzymes for the Homeland Defense: Optimizing Phosphotriesterase for the Hydrolysis of Organophosphate Nerve Agents
Author:
Affiliation:
1. Department of Chemistry, P.O. Box 30012, Texas A&M University, College Station, Texas 77842, United States
2. U.S. Army Edgewood Chemical Biological Center, 5183 Blackhawk Road, Aberdeen Proving Ground, Maryland 21010-5424, United States
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi300811t
Reference36 articles.
1. Inactivation of organophosphorus nerve agents by the phosphotriesterase from Pseudomonas diminuta
2. Protection against tabun toxicity in mice by prophylaxis with an enzyme hydrolyzing organophosphate esters
3. Limits of diffusion in the hydrolysis of substrates by the phosphotriesterase from Pseudomonas diminuta
4. Stereoselective Hydrolysis of Organophosphate Nerve Agents by the Bacterial Phosphotriesterase
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