N-Acylthiadiazolines, a New Class of Liver X Receptor Agonists with Selectivity for LXRβ-Reference-Cited by-同舟云学术

N-Acylthiadiazolines, a New Class of Liver X Receptor Agonists with Selectivity for LXRβ

Published:2007-08-01 Issue:17 Volume:50 Page:4255-4259
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Molteni Valentina¹,Li Xiaolin¹,Nabakka Juliet¹,Liang Fang¹,Wityak John¹,Koder Alan¹,Vargas Leo¹,Romeo Russell¹,Mitro Nico¹,Mak Puiying A.¹,Seidel H. Martin¹,Haslam Jennifer A.¹,Chow Donald¹,Tuntland Tove¹,Spalding Tracy A.¹,Brock Ansgar¹,Bradley Michelle¹,Castrillo Antonio¹,Tontonoz Peter¹,Saez Enrique¹

Affiliation:

1. Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, and Howard Hughes Medical Institute and Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California 90095

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070453f

Reference28 articles.

1. LXRS AND FXR: The Yin and Yang of Cholesterol and Fat Metabolism

2. Liver X Receptor Signaling Pathways in Cardiovascular Disease

3. An oxysterol signalling pathway mediated by the nuclear receptor LXRα

4. The nuclear receptor LXR is a glucose sensor

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