Efficient Large-Scale Synthesis of a 2,4,5-Triarylimidazoline MDM2 Antagonist-Reference-Cited by-同舟云学术

Efficient Large-Scale Synthesis of a 2,4,5-Triarylimidazoline MDM2 Antagonist

Published:2012-11-27 Issue:12 Volume:16 Page:1940-1946
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Shu Lianhe¹,Gu Chen¹,Dong Yan¹,Brinkman Robert¹

Affiliation:

1. Process Research and Synthesis, Pharma Research and Early Development (pRED), Hoffmann-La Roche, Inc., 340 Kingsland Street, Nutley, New Jersey 07110, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op300294g

Reference23 articles.

1. Surfing the p53 network

2. p53, the Cellular Gatekeeper for Growth and Division

3. The MDM2 gene amplification database

4. Functions of the MDM2 oncoprotein

5. Retinoids: present role and future potential

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