Molecular Modeling Based Approach to Potent P2−P4 Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease-Reference-Cited by-同舟云学术

Molecular Modeling Based Approach to Potent P2−P4 Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease

Published:2008-03-14 Issue:14 Volume:130 Page:4607-4609
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Liverton Nigel J.¹,Holloway M. Katharine¹,McCauley John A.¹,Rudd Michael T.¹,Butcher John W.¹,Carroll Steven S.¹,DiMuzio Jillian¹,Fandozzi Christine¹,Gilbert Kevin F.¹,Mao Shi-Shan¹,McIntyre Charles J.¹,Nguyen Kevin T.¹,Romano Joseph J.¹,Stahlhut Mark¹,Wan Bang-Lin¹,Olsen David B.¹,Vacca Joseph P.¹

Affiliation:

1. Departments of Medicinal Chemistry, Antiviral Research, Drug Metabolism, and Molecular Systems, Merck Research Laboratories, West Point, Pennsylvania 19486

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja711120r

Reference21 articles.

1. Pathogenesis of hepatitis C—associated hepatocellular carcinoma

2. Liver disease as a major cause of death among HIV infected patients: role of hepatitis C and B viruses and alcohol

3. Control of Hepatitis C: A Medicinal Chemistry Perspective

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