Design and Synthesis of Inhaled p38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease-Reference-Cited by-同舟云学术

Design and Synthesis of Inhaled p38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease

Published:2011-10-28 Issue:22 Volume:54 Page:7797-7814
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Millan David S.¹,Bunnage Mark E.¹,Burrows Jane L.¹,Butcher Kenneth J.¹,Dodd Peter G.¹,Evans Timothy J.¹,Fairman David A.¹,Hughes Samantha J.¹,Kilty Iain C.¹,Lemaitre Arnaud¹,Lewthwaite Russell A.¹,Mahnke Axel¹,Mathias John P.¹,Philip James¹,Smith Robert T.¹,Stefaniak Mark H.¹,Yeadon Michael¹,Phillips Christopher¹

Affiliation:

1. Worldwide Medicinal Chemistry, ∥Allergy and Respiratory Research Unit, ⊥Department of Pharmacokinetics, Dynamics, and Metabolism, #Department of Drug Safety, and ∞Department of Pharmaceutical Sciences, Pfizer Global Research and Development, Sandwich Laboratories, Ramsgate Road, Sandwich, Kent, CT13 9NJ, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200677b

Reference28 articles.

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4. Oral p38 Mitogen-Activated Protein Kinase Inhibition With BIRB 796 for Active Crohn’s Disease: A Randomized, Double-Blind, Placebo-Controlled Trial

5. Selective p38α Inhibitors Clinically Evaluated for the Treatment of Chronic Inflammatory Disorders

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