Second-Generation Antibacterial Benzimidazole Ureas: Discovery of a Preclinical Candidate with Reduced Metabolic Liability-Reference-Cited by-同舟云学术

Second-Generation Antibacterial Benzimidazole Ureas: Discovery of a Preclinical Candidate with Reduced Metabolic Liability

Published:2014-10-28 Issue:21 Volume:57 Page:8792-8816
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Grillot Anne-Laure¹,Tiran Arnaud Le¹,Shannon Dean¹,Krueger Elaine¹,Liao Yusheng¹,O’Dowd Hardwin¹,Tang Qing¹,Ronkin Steve¹,Wang Tiansheng¹,Waal Nathan¹,Li Pan¹,Lauffer David¹,Sizensky Emmanuelle¹,Tanoury Jerry¹,Perola Emanuele¹,Grossman Trudy H.¹,Doyle Tim¹,Hanzelka Brian¹,Jones Steven¹,Dixit Vaishali¹,Ewing Nigel¹,Liao Shengkai¹,Boucher Brian¹,Jacobs Marc¹,Bennani Youssef¹,Charifson Paul S.¹

Affiliation:

1. Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, Massachusetts 02210, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500563g

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