Two Novel α-Neurotoxins Isolated from the Taipan Snake, Oxyuranus scutellatus, Exhibit Reduced Affinity for Nicotinic Acetylcholine Receptors in Brain and Skeletal Muscle-Reference-Cited by-同舟云学术

Two Novel α-Neurotoxins Isolated from the Taipan Snake, Oxyuranus scutellatus, Exhibit Reduced Affinity for Nicotinic Acetylcholine Receptors in Brain and Skeletal Muscle

Published:1996-01-01 Issue:24 Volume:35 Page:7910-7916
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Zamudio Fernando¹,Wolf Kathleen M.¹,Martin Brian M.¹,Possani Lourival D.¹,Chiappinelli Vincent A.¹

Affiliation:

1. Department of Molecular Recognition and Structural Biology, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Avenida Universidad 2001, Cuernavaca, 62271 Mexico, Molecular Neurogenetics Unit, Clinical Neuroscience Branch, National Institute of Mental Health, Building 49 B1EE16, Bethesda, Maryland 20892, and Department of Pharmacological and Physiological Science, St. Louis University School of Medicine, St. Louis, Missouri 63104

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi9600761

Reference37 articles.

1. α-Cobratoxin blocks the nicotinic acetylcholine receptor in rat hippocampal neurons

2. Homomeric and native α7 acetylcholine receptors exhibit remarkably similar but non-identical pharmacological properties, suggesting that the native receptor is a heteromeric protein complex

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