Efficient Synthesis of Symmetrical α,α-Disubstituted β-Amino Acids and α,α-Disubstituted Aldehydes via Dialkylation of Nucleophilic β-Alanine Equivalent-Reference-Cited by-同舟云学术

Efficient Synthesis of Symmetrical α,α-Disubstituted β-Amino Acids and α,α-Disubstituted Aldehydes via Dialkylation of Nucleophilic β-Alanine Equivalent

Published:2010-02-08 Issue:5 Volume:75 Page:1717-1722
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Lin Daizong¹,Deng Guanghui¹,Wang Jiang¹,Ding Xiao¹,Jiang Hualiang¹,Liu Hong¹

Affiliation:

1. The Center for Drug Discovery and Design, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People’s Republic of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo902699t

Reference40 articles.

1. Application of 3D QSAR CoMFA/CoMSIA and in silico docking studies on novel renin inhibitors against cardiovascular diseases

2. 2-propyl-1-aminopentane, its deamination by monoamine oxidase and semicarbazide-sensitive amine oxidase, conversion to valproic acid and behavioral effects

3. Biosynthetic Characterization and Chemoenzymatic Assembly of the Cryptophycins. Potent Anticancer Agents from Nostoc Cyanobionts

4. dAikins, J. A.; Briggs, B. S.; Zhang, T. Y.; Zmijewski, M. J.Patent Application WO200023429, 2000.

5. The Synthesis of a Geminally Perfluoro-tert-butylated β-Amino Acid and its Protected Forms as a Potential Pharmacokinetic Modulator and Reporter for Peptide-Based Pharmaceuticals

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Modular synthesis of congested β^2,2-amino acids via the merger of photocatalysis and oxidative functionalisations;Chemical Communications;2024

2. Chemical Resolution of C,N-Unprotected α-Substituted β-Amino Acids Using Stable and Recyclable Proline-Derived Chiral Ligands;The Journal of Organic Chemistry;2018-07-13

3. Configurationally Stable (S )- and (R )-α-Methylproline-Derived Ligands for the Direct Chemical Resolution of Free Unprotected β3 -Amino Acids;European Journal of Organic Chemistry;2018-04-20

4. Asymmetric Synthesis of 3, 5-Disubstituted Prolines;Chinese Journal of Organic Chemistry;2018

5. Copper(II)-mediated intermolecular amination of inert C(sp3)H bonds with simple alkylamines to construct α,α-disubstituted β-amino acid derivatives;Tetrahedron Letters;2017-03