Metabolomics Profiling of Cell Culture Media Leading to the Identification of Riboflavin Photosensitized Degradation of Tryptophan Causing Slow Growth in Cell Culture-Reference-Cited by-同舟云学术

Metabolomics Profiling of Cell Culture Media Leading to the Identification of Riboflavin Photosensitized Degradation of Tryptophan Causing Slow Growth in Cell Culture

Published:2011-06-13 Issue:13 Volume:83 Page:5422-5430
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Zang Li¹,Frenkel Ruth¹,Simeone Jeffrey¹,Lanan Maureen¹,Byers Mark¹,Lyubarskaya Yelena¹

Affiliation:

1. Analytical Development Department and ‡Manufacturing Sciences Department, BiogenIdec, Cambridge, Massachusetts 02142, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac2009492

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1. Production of recombinant protein therapeutics in cultivated mammalian cells

2. High cell density and high monoclonal antibody production through medium design and rational control in a bioreactor

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4. Amplification and expression of recombinant genes in serum‐independent Chinese hamster ovary cells

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