1. College of Pharmacy, Chungbuk National University, 48, Gaesin-dong, Heungduk-gu, Cheongju, Chungbuk 361-763, Korea, College of Oriental Medicine, Kyungwon University 65, Bukjeong-Dong, Sujeong-gu, Seongnam, Gyeonggii 461-701, Korea, and Korea Research Institute of Bioscience and Biotechnology, 52, Oun-dong, Yusong-gu, Taejon, 305-333, Korea