Identification of a New G-Quadruplex Motif in the KRAS Promoter and Design of Pyrene-Modified G4-Decoys with Antiproliferative Activity in Pancreatic Cancer Cells-Reference-Cited by-同舟云学术

Identification of a New G-Quadruplex Motif in the KRAS Promoter and Design of Pyrene-Modified G4-Decoys with Antiproliferative Activity in Pancreatic Cancer Cells

Published:2008-12-19 Issue:2 Volume:52 Page:564-568
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cogoi Susanna¹,Paramasivam Manikandan¹,Filichev Vyacheslav¹,Géci Imrich¹,Pedersen Erik B.¹,Xodo Luigi E.¹

Affiliation:

1. Department of Biomedical Science and Technology, School of Medicine, P.le Kolbe 4, 33100 Udine, Italy, Institute of Fundamental Sciences, Massey University, Palmerston North, New Zealand, Nucleic Acid Center, Institute of Physics and Chemistry, University of Southern Denmark, DK-5230 Odense M, Denmark

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800874t

Reference23 articles.

1. Pancreatic cancer biology and genetics

2. Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects

3. Gene therapy developments for pancreatic cancer

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