Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity:  Design, Synthesis, and X-ray Cocrystal Structure

Author:

Canan Koch Stacie S.1,Thoresen Lars H.1,Tikhe Jayashree G.1,Maegley Karen A.1,Almassy Robert J.1,Li Jianke1,Yu Xiao-Hong1,Zook Scott E.1,Kumpf Robert A.1,Zhang Cathy1,Boritzki Theodore J.1,Mansour Rena N.1,Zhang Kanyin E.1,Ekker Anne1,Calabrese Chris R.1,Curtin Nicola J.1,Kyle Suzanne1,Thomas Huw D.1,Wang Lan-Zhen1,Calvert A. Hilary1,Golding Bernard T.1,Griffin Roger J.1,Newell David R.1,Webber Stephen E.1,Hostomsky Zdenek1

Affiliation:

1. Pfizer Global Research and Development, La Jolla/Agouron Pharmaceuticals, Inc., 10770 Science Center Drive, San Diego, California 92121, and University of Newcastle, Newcastle upon Tyne, NE2 4HH, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3