Structure-Based Lead Optimization and Biological Evaluation of BAX Direct Activators as Novel Potential Anticancer Agents-Reference-Cited by-同舟云学术

Structure-Based Lead Optimization and Biological Evaluation of BAX Direct Activators as Novel Potential Anticancer Agents

Published:2015-02-25 Issue:5 Volume:58 Page:2135-2148
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Stornaiuolo Mariano¹,La Regina Giuseppe²,Passacantilli Sara²,Grassia Gianluca¹,Coluccia Antonio²,La Pietra Valeria¹,Giustiniano Mariateresa¹,Cassese Hilde¹,Di Maro Salvatore¹,Brancaccio Diego¹,Taliani Sabrina³,Ialenti Armando¹,Silvestri Romano²,Martini Claudia³,Novellino Ettore¹,Marinelli Luciana¹

Affiliation:

1. Dipartimento di Farmacia, Università di Napoli “Federico II”, via D. Montesano 49, 80131 Naples, Italy

2. Istituto Pasteur—Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, Piazzale Aldo Moro 5, I-00185 Roma, Italy

3. Dipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy

Funder

Ministero dell'Istruzione, dell'Università e della Ricerca

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501123r

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2. Mitochondria and cell death: outer membrane permeabilization and beyond