Nucleosides and Nucleotides. 175. Structural Requirements of the Sugar Moiety for the Antitumor Activities of New Nucleoside Antimetabolites, 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)cytosine and -uracil-Reference-Cited by-同舟云学术

Nucleosides and Nucleotides. 175. Structural Requirements of the Sugar Moiety for the Antitumor Activities of New Nucleoside Antimetabolites, 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)cytosine and -uracil

Published:1998-06-18 Issue:15 Volume:41 Page:2892-2902
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hattori Hideshi¹,Nozawa Eisuke¹,Iino Tomoharu¹,Yoshimura Yuichi¹,Shuto Satoshi¹,Shimamoto Yuji¹,Nomura Makoto¹,Fukushima Masakazu¹,Tanaka Motohiro¹,Sasaki Takuma¹,Matsuda Akira¹

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan, Cancer Research Laboratory-2, Hanno Research Center, Taiho Pharmaceutical Company Ltd., Hanno 357-8527, Japan, and Cancer Research Institute, Kanazawa University, Takara-machi, Kanazawa 920-0934, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9801814

Reference24 articles.

1. Nucleosides and nucleotides. 152. 1-(3-C-Ethynyl-β-D-ribo-pentofuranosyl)uracil as a broad spectrum antitumor nucleoside

2. Nucleosides and Nucleotides. 158. 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)- cytosine, 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)uracil, and Their Nucleobase Analogues as New Potential Multifunctional Antitumor Nucleosides with a Broad Spectrum of Activity

3. Antitumor mechanisms of 3′-ethynyluridine and 3′-ethynylcytidine as RNA synthesis inhibitors: development and characterization of 3′-ethynyluridine- resistant cells

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