Selective Inhibition of ICAM-1 and E-Selectin Expression in Human Endothelial Cells. 2. Aryl Modifications of 4-(Aryloxy)thieno[2,3-c]pyridines with Fine-Tuning at C-2 Carbamides

Author:

Zhu Gui-Dong1,Arendsen David L.1,Gunawardana Indrani W.1,Boyd Steven A.1,Stewart Andrew O.1,Fry Dennis G.1,Cool Barbara L.1,Kifle Lemma1,Schaefer Verlyn1,Meuth Joseph1,Marsh Kennan C.1,Kempf-Grote Anita J.1,Kilgannon Patrick1,Gallatin W. Michael1,Okasinski Gregory F.1

Affiliation:

1. Metabolic Diseases Research, Pharmaceutical Products Division, Abbott Laboratories, Department 04MJ, Building AP10, 100 Abbott Park Road, Abbott Park, Illinois 60064-6101, and ICOS Corporation, 22021 20th Avenue SE, Bothell, Washington 98021

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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