Characterization of Small Protein Aggregates and Oligomers Using Size Exclusion Chromatography with Online Detection by Native Electrospray Ionization Mass Spectrometry-Reference-Cited by-同舟云学术

Characterization of Small Protein Aggregates and Oligomers Using Size Exclusion Chromatography with Online Detection by Native Electrospray Ionization Mass Spectrometry

Published:2014-10-27 Issue:21 Volume:86 Page:10692-10699
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Muneeruddin Khaja¹,Thomas John J.²,Salinas Paul A.²,Kaltashov Igor A.¹

Affiliation:

1. Department of Chemistry, University of Massachusetts−Amherst, Amherst, Massachusetts 01003, United States

2. Department of Analytical Development, Shire, 300 Shire Way, Lexington, Massachusetts 02421, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac502590h

Reference37 articles.

1. Amyloid diseases: Abnormal protein aggregation in neurodegeneration

2. Protein Denaturation and Aggregation: Cellular Responses to Denatured and Aggregated Proteins

3. Amyloidogenesis in its biological environment: challenging a fundamental issue in protein misfolding diseases

4. Minimizing immunogenicity of biopharmaceuticals by controlling critical quality attributes of proteins

5. Principles, approaches, and challenges for predicting protein aggregation rates and shelf life

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