The Basic Helix−Loop−Helix Region of Human Neurogenin 1 Is a Monomeric Natively Unfolded Protein Which Forms a “Fuzzy” Complex upon DNA Binding-Reference-Cited by-同舟云学术

The Basic Helix−Loop−Helix Region of Human Neurogenin 1 Is a Monomeric Natively Unfolded Protein Which Forms a “Fuzzy” Complex upon DNA Binding

Published:2010-02-08 Issue:8 Volume:49 Page:1577-1589
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Aguado-Llera David¹,Goormaghtigh Erik²,de Geest Natalie³⁴,Quan Xiao-Jiang³⁴,Prieto Alicia⁵,Hassan Bassen A.³⁴,Gómez Javier¹,Neira José L.¹⁶

Affiliation:

1. Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, 03202 Elche (Alicante), Spain

2. Centre for Structural Biology and Bioinformatics, Structure and Function of Biological Membranes, Université Libre de Bruxelles, B1050 Brussels, Belgium

3. Department of Molecular and Developmental Genetics, VIB, 3000 Leuven, Belgium

4. Center for Human Genetics, KU Leuven School of Medicine, 3000 Leuven, Belgium

5. Centro de Investigaciones Biológicas, CSIC, 28006 Madrid, Spain

6. Biocomputation and Complex Systems Physics Institute, 50009 Zaragoza, Spain

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi901616z

Reference73 articles.

1. Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

2. Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms

3. Crystal structure of MyoD bHLH domain-DNA complex: Perspectives on DNA recognition and implications for transcriptional activation

4. Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition

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