2-Substituted Aminopyrido[2,3-d]pyrimidin-7(8H)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer Activity-Reference-Cited by-同舟云学术

2-Substituted Aminopyrido[2,3-d]pyrimidin-7(8H)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer Activity

Published:1998-07-24 Issue:17 Volume:41 Page:3276-3292
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Klutchko Sylvester R.¹,Hamby James M.¹,Boschelli Diane H.¹,Wu Zhipei¹,Kraker Alan J.¹,Amar Aneesa M.¹,Hartl Brian G.¹,Shen Cynthia¹,Klohs Wayne D.¹,Steinkampf Randall W.¹,Driscoll Denise L.¹,Nelson James M.¹,Elliott William L.¹,Roberts Billy J.¹,Stoner Chad L.¹,Vincent Patrick W.¹,Dykes Donald J.¹,Panek Robert L.¹,Lu Gina H.¹,Major Terry C.¹,Dahring Tawny K.¹,Hallak Hussein¹,Bradford Laura A.¹,Showalter H. D. Hollis¹,Doherty Annette M.¹

Affiliation:

1. Departments of Chemistry, Cancer Research, Vascular and Cardiac Diseases, and Pharmacokinetics and Drug Metabolism, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan 48105, and Southern Research Institute, Birmingham, Alabama 35255

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9802259

Reference44 articles.

1. Growth factors and cell proliferation

2. PDGF ligand and receptor gene expression during repair of arterial injury.

3. The biology of platelet-derived growth factor

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