Divergent Total Synthesis of Triptolide, Triptonide, Tripdiolide, 16-Hydroxytriptolide, and Their Analogues
Author:
Affiliation:
1. Department of Medical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhangjiang Hi-Tech Park, Shanghai 201203, P.R. China
Funder
National Natural Science Foundation of China
Science and Technology Commission of Shanghai Municipality
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo501744j
Reference50 articles.
1. Tumor inhibitors. LXXIV. Triptolide and tripdiolide, novel antileukemic diterpenoid triepoxides from Tripterygium wilfordii
2. aHuang, S.The Saint Peasant’s Scripture of Materia Medica (18357);Publishing House for Chinese Medicine Classics:Beijing, republished in 1982; p309.
3. Mechanism of triptolide-induced apoptosis: effect on caspase activation and Bid cleavage and essentiality of the hydroxyl group of triptolide
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