A Novel Series of 2,6,7-Substituted 2,3-Dihydro-1,4-Benzodioxin and 2,6,7-Substituted 1,4-Benzodioxin Derivatives as Lipid Peroxidation Inhibitors. Structure−Activity Relationships for High Inhibition of Human Low-Density Lipoprotein Peroxidation-Reference-Cited by-同舟云学术

A Novel Series of 2,6,7-Substituted 2,3-Dihydro-1,4-Benzodioxin and 2,6,7-Substituted 1,4-Benzodioxin Derivatives as Lipid Peroxidation Inhibitors. Structure−Activity Relationships for High Inhibition of Human Low-Density Lipoprotein Peroxidation

Published:2001-10-13 Issue:23 Volume:44 Page:3904-3914
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Thiéry Valérie¹,Coudert Gérard¹,Bizot-Espiard Jean-Guy¹,Pfeiffer Bruno¹,Renard Pierre¹,Lindenbaum Albert¹,Guillaumet Gérald¹

Affiliation:

1. Institut de Chimie Organique et Analytique, UMR CNRS 6005, Université d'Orléans, B.P. 6759, F-45067 Orléans Cedex 2, France, Laboratoire de Génie Protéique et Cellulaire, Université de La Rochelle, Avenue Michel Crépeau, F-17042 La Rochelle Cedex 1, France, Service de Biochimie, Hopital Antoine Béclere, 92141 Clamart, France, IRI Servier, 6 Place des Pléiades, F-92415 Courbevoie Cedex, France, and ADIR, 1 rue Carle Hébert, F-92415 Courbevoie Cedex, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0108045

Reference60 articles.

1. Role of oxidized low density lipoprotein in atherogenesis.

2. Effect of oral supplementation with D-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation.

3. The oxidation hypothesis of atherosclerosis

4. Low Density Lipoprotein Oxidation and Its Pathobiological Significance

5. Oxidation of low density lipoproteins in the pathogenesis of atherosclerosis

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