Structure–Activity Relationships, Ligand Efficiency, and Lipophilic Efficiency Profiles of Benzophenone-Type Inhibitors of the Multidrug Transporter P-Glycoprotein-Reference-Cited by-同舟云学术

Structure–Activity Relationships, Ligand Efficiency, and Lipophilic Efficiency Profiles of Benzophenone-Type Inhibitors of the Multidrug Transporter P-Glycoprotein

Published:2012-03-27 Issue:7 Volume:55 Page:3261-3273
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jabeen Ishrat¹,Pleban Karin¹,Rinner Uwe²,Chiba Peter³,Ecker Gerhard F.¹

Affiliation:

1. University of Vienna, Department of Medicinal Chemistry, Althanstrasse 14, 1090, Vienna, Austria

2. University of Vienna, Department of Organic Chemistry, Währingerstrasse 38, 1090, Vienna, Austria

3. Medical University of Vienna, Institute of Medical Chemistry, Währingerstrasse 10, 1090, Vienna, Austria

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201705f

Reference59 articles.

1. Membrane transporters in drug development

2. Role of membrane transporters in the safety profile of drugs

3. Targeting multidrug resistance in cancer

4. The ATP-Binding Cassette Transporters and Their Implication in Drug Disposition: A Special Look at the Heart

5. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox)

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