Competitive Antagonism of AMPA Receptors by Ligands of Different Classes: Crystal Structure of ATPO Bound to the GluR2 Ligand-Binding Core, in Comparison with DNQX-Reference-Cited by-同舟云学术

Competitive Antagonism of AMPA Receptors by Ligands of Different Classes: Crystal Structure of ATPO Bound to the GluR2 Ligand-Binding Core, in Comparison with DNQX

Published:2002-12-12 Issue:2 Volume:46 Page:214-221
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hogner Anders¹,Greenwood Jeremy R.¹,Liljefors Tommy¹,Lunn Marie-Louise¹,Egebjerg Jan¹,Larsen Ingrid K.¹,Gouaux Eric¹,Kastrup Jette S.¹

Affiliation:

1. Department of Medicinal Chemistry, Royal Danish School of Pharmacy, Universitetsparken 2, DK 2100 Copenhagen, Denmark, Department for Molecular and Structural Biology, University of Aarhus, DK-8000 Aarhus, Denmark, Department of Biochemistry and Molecular Biophysics, Columbia University, 650 W. 168th Street, New York, New York 10032, and Howard Hughes Medical Institute, Columbia University, New York, New York 10032

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020989v

Reference47 articles.

1. Glutamate in CNS disorders as a target for drug development: an update

2. Cloned Glutamate Receptors

3. Mechanisms for Activation and Antagonism of an AMPA-Sensitive Glutamate Receptor

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