(2R)-2-Ethylchromane-2-carboxylic Acids: Discovery of Novel PPARα/γ Dual Agonists as Antihyperglycemic and Hypolipidemic Agents
Author:
Affiliation:
1. Departments of Medicinal Chemistry, Metabolic Disorders, Atherosclerosis and Endocrinology, and Drug Metabolism, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065-0900
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm030621d
Reference52 articles.
1. New drug targets for type 2 diabetes and the metabolic syndrome
2. New Perspectives into the Molecular Pathogenesis and Treatment of Type 2 Diabetes
3. Management of Dyslipidemia in Children and Adolescents With Diabetes
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