Molecular Dynamics Simulations for Complexation of DNA with 2 kDa PEI Reveal Profound Effect of PEI Architecture on Complexation-Reference-Cited by-同舟云学术

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Molecular Dynamics Simulations for Complexation of DNA with 2 kDa PEI Reveal Profound Effect of PEI Architecture on Complexation

Published:2012-02-15 Issue:8 Volume:116 Page:2405-2413
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Sun Chongbo¹,Tang Tian¹,Uludaǧ Hasan²³⁴

Affiliation:

1. Department of Mechanical Engineering, University of Alberta, Edmonton, Canada

2. Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Canada

3. Department of Biomedical Engineering, University of Alberta, Edmonton, Canada

4. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Canada

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jp211716v

Reference34 articles.

1. Nonviral Gene Therapy: The Promise of Genes as Pharmaceutical Products

2. Synthetic DNA delivery systems

3. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

4. Poly(ethylenimine) and its role in gene delivery

5. Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle

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1. Beyond Lipids: Exploring Advances in Polymeric Gene Delivery in the Lipid Nanoparticles Era;Advanced Materials;2024-06-19

2. Automated Parameterization of Coarse-Grained Polyethylenimine under a Martini Framework;Journal of Chemical Information and Modeling;2023-07-10

3. Polycation-Mediated Transfection: Mechanisms of Internalization and Intracellular Trafficking;Biomacromolecules;2021-09-09

4. Modeling Uptake of Polyethylenimine/Short Interfering RNA Nanoparticles in Breast Cancer Cells Using Machine Learning;Advanced NanoBiomed Research;2021-07-08

5. In silico prediction of the in vitro behavior of polymeric gene delivery vectors;Nanoscale;2021

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