Mycangimycin, a Polyene Peroxide from a Mutualist Streptomyces sp.

Author:

Oh Dong-Chan1,Scott Jarrod J.1,Currie Cameron R.1,Clardy Jon1

Affiliation:

1. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, and Department of Bacteriology, University of Wisconsin−Madison, Madison, Wisconsin 53706

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference15 articles.

1. Combined chemical defenses against an insect-fungal complex

2. Bacterial Protection of Beetle-Fungus Mutualism

3. Mycangimycin (1): yellow powder; [α]24D−134 (c0.033, THF); IR (neat) υmax3353, 2958, 2884, 1721, 1641, 1438, 1369, 1345, 1191, 1117, 1067, 956, 852 cm−1; UV (THF) λmax(log ε) 338 (4.2), 355 (4.3), 374 (4.4), 395 (4.3) nm; NMR spectral data, see Table1; HR-CI-TOFMS [M + Na]+m/z353.1565 (C20H24O4) calcd [M + Na]+353.1572.

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