Antibacterial Activities of Aminoglycoside Antibiotics-Derived Cationic Amphiphiles. Polyol-Modified Neomycin B-, Kanamycin A-, Amikacin-, and Neamine-Based Amphiphiles with Potent Broad Spectrum Antibacterial Activity-Reference-Cited by-同舟云学术

Antibacterial Activities of Aminoglycoside Antibiotics-Derived Cationic Amphiphiles. Polyol-Modified Neomycin B-, Kanamycin A-, Amikacin-, and Neamine-Based Amphiphiles with Potent Broad Spectrum Antibacterial Activity

Published:2010-04-07 Issue:9 Volume:53 Page:3626-3631
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bera Smritilekha¹,Zhanel George G.²,Schweizer Frank¹²

Affiliation:

1. Department of Chemistry, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada

2. Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, R3E 3P4, Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm1000437

Reference60 articles.

1. Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

2. The Crisis in Antibiotic Resistance

3. Binding of polycationic antibiotics and polyamines to lipopolysaccharides of Pseudomonas aeruginosa

4. Interaction of polycationic antibiotics with Pseudomonas aeruginosa lipopolysaccharide and lipid A studied by using dansyl-polymyxin

5. Mechanism of bactericidal action of aminoglycosides

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