New Interfacial Microtubule Inhibitors of Marine Origin, PM050489/PM060184, with Potent Antitumor Activity and a Distinct Mechanism-Reference-Cited by-同舟云学术

New Interfacial Microtubule Inhibitors of Marine Origin, PM050489/PM060184, with Potent Antitumor Activity and a Distinct Mechanism

Published:2013-08-01 Issue:9 Volume:8 Page:2084-2094
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Pera Benet¹,Barasoain Isabel¹,Pantazopoulou Areti¹,Canales Angeles¹,Matesanz Ruth¹,Rodriguez-Salarichs Javier¹,García-Fernandez Luis F.²,Moneo Victoria²,Jiménez-Barbero Jesús¹,Galmarini Carlos M.²,Cuevas Carmen²,Peñalva Miguel A.¹,Díaz J. Fernando¹,Andreu José M.¹

Affiliation:

1. Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain

2. PharmaMar S.A., Avda de los Reyes 1, Polígono Industrial La Mina, Colmenar Viejo, 28770 Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb400461j

Reference64 articles.

1. How Do Microtubule-Targeted Drugs Work? An Overview

2. Promotion of microtubule assembly in vitro by taxol

3. Relationships between the structure of taxol analogs and their antimitotic activity

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