Molecular Properties and Pharmacokinetic Behavior of Cetirizine, a Zwitterionic H1-Receptor Antagonist-Reference-Cited by-同舟云学术

Molecular Properties and Pharmacokinetic Behavior of Cetirizine, a Zwitterionic H1-Receptor Antagonist

Published:1998-02-14 Issue:6 Volume:41 Page:853-863
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pagliara Alessandra¹,Testa Bernard¹,Carrupt Pierre-Alain¹,Jolliet Pascale¹,Morin Christophe¹,Morin Didier¹,Urien Saïk¹,Tillement Jean-Paul¹,Rihoux Jean-Pierre¹

Affiliation:

1. Institut de Chimie Thérapeutique, Université de Lausanne, BEP, CH-1015 Lausanne, Switzerland, Laboratoire de Pharmacologie, Faculté de Médecine de Créteil, Université de Paris XII, F-94010 Créteil, France, and UCB Pharma, B-1420 Braine-l'Alleud, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9704311

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3. A low distribution volume as a determinant of efficacy and safety for histamine (H1antagonists

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