Novel Benzylidene-9(10H)-anthracenones as Highly Active Antimicrotubule Agents. Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization-Reference-Cited by-同舟云学术

Novel Benzylidene-9(10H)-anthracenones as Highly Active Antimicrotubule Agents. Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization

Published:2003-06-21 Issue:15 Volume:46 Page:3382-3394
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Prinz Helge¹,Ishii Yukihito¹,Hirano Takeo¹,Stoiber Thomas¹,Camacho Gomez Juan A.¹,Schmidt Peter¹,Düssmann Heiko¹,Burger Angelika M.¹,Prehn Jochen H. M.¹,Günther Eckhard G.¹,Unger Eberhard¹,Umezawa Kazuo¹

Affiliation:

1. Institute of Pharmaceutical and Medicinal Chemistry, Westphalian Wilhelms-University, Hittorfstrasse 58-62, D-48149 Münster, Germany, Zentaris AG, Weismüllerstrasse 45, D-60314 Frankfurt, Germany, Oncotest GmbH, Am Flughafen 12-14, D-79108 Freiburg, Germany, Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-0061, Japan, Interdisciplinary Center for Clinical Research, Research Group “Apoptosis and Cell Death”, Westphalian Wilhelms...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0307685

Reference52 articles.

1. Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle

2. New inhibitors of tubulin polymerisation

3. Interactions of colchicine with tubulin

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