Rationale, Design, and Synthesis of Novel Phenyl Imidazoles as Opioid Receptor Agonists for Gastrointestinal Disorders-Reference-Cited by-同舟云学术

Rationale, Design, and Synthesis of Novel Phenyl Imidazoles as Opioid Receptor Agonists for Gastrointestinal Disorders

Published:2004-09-04 Issue:21 Volume:47 Page:5009-5020
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Breslin Henry J.¹,Miskowski Tamara A.¹,Rafferty Bryan M.¹,Coutinho Santosh V.¹,Palmer Jeffrey M.¹,Wallace Nathaniel H.¹,Schneider Craig R.¹,Kimball Edward S.¹,Zhang Sui-Po¹,Li Jian¹,Colburn Raymond W.¹,Stone Dennis J.¹,Martinez Rebecca P.¹,He Wei¹

Affiliation:

1. Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh and McKean Roads, P.O. Box 776, Spring House, Pennsylvania 19477-0776

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030548r

Reference28 articles.

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2. (a) Fries, D. S. Analgesics. InPrinciples of Medicinal Chemistry, 4th ed.; Foye, W. O., Lemke, T. L., Williams, D. A., Eds.; Willimams and Wilkins: Baltimore, MD, 1995; pp 247−269;

3. (b) Aldrich, J. V. "Analgesics"Burger's Medicinal Chemistry and Drug Discovery,5th ed., Volume 3: Therapeutic Agents, John Wiley & Sons: New York, 1996; pp 321−441.

4. Riviere, J. M.; Junien, J.L. Opioid Receptors: Targets for New Gastrointestinal Drug Development. InDrug Development: MolecularTargets for GI Diseases; Gaginella, T. S., Guglietta, A., Eds.; Humana Press Inc., Totowa, NJ, pp 203−238.

5. Identification of two related pentapeptides from the brain with potent opiate agonist activity

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