Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 2. Mechanism of Inhibition and Structure-Based Improvement of Pharmaceutical Properties-Reference-Cited by-同舟云学术

Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 2. Mechanism of Inhibition and Structure-Based Improvement of Pharmaceutical Properties

Published:2001-03-21 Issue:8 Volume:44 Page:1202-1210
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Liu Gang¹,Huth Jeffrey R.¹,Olejniczak Edward T.¹,Mendoza Renaldo¹,DeVries Peter¹,Leitza Sandra¹,Reilly Edward B.¹,Okasinski Gregory F.¹,Fesik Stephen W.¹,von Geldern Thomas W.¹

Affiliation:

1. Metabolic Disease Research and Research NMR, Pharmaceutical Products Division, Abbott Laboratories, Abbott Park, Illinois 60064-6098

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000503f

Reference27 articles.

1. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

2. Integrins: Versatility, modulation, and signaling in cell adhesion

3. Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules

4. Leukocyte-endothelial adhesion molecules

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