Characterization of Molecular Interactions between ACP and Halogenase Domains in the Curacin A Polyketide Synthase

Author:

Busche Alena1,Gottstein Daniel1,Hein Christopher1,Ripin Nina1,Pader Irina1,Tufar Peter1,Eisman Eli B.2,Gu Liangcai2,Walsh Christopher T.,Sherman David H.2,Löhr Frank1,Güntert Peter134,Dötsch Volker1

Affiliation:

1. Institute of Biophysical Chemistry, Goethe University Frankfurt and Center for Biomolecular Magnetic Resonance, Max-von-Laue Str. 9, 60438 Frankfurt am Main, Germany

2. Life Sciences Institute, Departments of Medicinal Chemistry, Chemistry, and Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, United States

3. Frankfurt Institute for Advanced Studies, Goethe University Frankfurt, Ruth-Moufang-Str. 1, 60438 Frankfurt am Main, Germany

4. Center for Priority Areas, Tokyo Metropolitan University, 1-1 minami-ohsawa, Hachioji, Tokyo 192-0397, Japan

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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