1. Nutritional Sciences, School of Applied Sciences, The University of Newcastle, P.O. Box 127 Ourimbah, NSW 2258, Australia, Wellcome Trust Centre of Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom, CSIRO Health Sciences and Nutrition, Adelaide SA 5000, Australia, and Department of Physiology, University of Adelaide, Adelaide SA 5000, Australia