Small-Molecule Inhibition of Androgen Receptor Dimerization as a Strategy against Prostate Cancer

Author:

Fu Weitao12,Yang Hao3,Hu Chenxian14,Liao Jianing1,Gong Zhou5,Zhang Minkui1,Yang Shuai56,Ye Shangxiang7,Lei Yixuan1,Sheng Rong18ORCID,Zhang Zhiguo39ORCID,Yao Xiaojun10ORCID,Tang Chun11ORCID,Li Dan18ORCID,Hou Tingjun1ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, Zhejiang, China

2. Department of Computer-Aided Drug Design, Jiangsu Vcare PharmaTech Co. Ltd., Nanjing 211800, China

3. Institute of Zhejiang University - Quzhou, Zhejiang University, Quzhou 324000, Zhejiang, China

4. Polytechnic Institute, Zhejiang University, Hangzhou 310015, Zhejiang, China

5. Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, Hubei, China

6. University of Chinese Academy of Sciences, Beijing 100049, China

7. Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China

8. Jinhua Institute of Zhejiang University, Jinhua 321000, Zhejiang, China

9. Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, Zhejiang, China

10. Dr. Neher’s Biophysics Laboratory for Innovative Drug Discovery, Macau Institute for Applied Research in Medicine and Health, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China

11. Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, and Center for Quantitate Biology, PKU-Tsinghua Center for Life Science, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

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