A Single Immunization with Spike-Functionalized Ferritin Vaccines Elicits Neutralizing Antibody Responses against SARS-CoV-2 in Mice-Reference-Cited by-同舟云学术

A Single Immunization with Spike-Functionalized Ferritin Vaccines Elicits Neutralizing Antibody Responses against SARS-CoV-2 in Mice

Published:2021-01-05 Issue:1 Volume:7 Page:183-199
ISSN:2374-7943
Container-title:ACS Central Science
language:en
Short-container-title:ACS Cent. Sci.

Author:

Powell Abigail E.¹^ORCID,Zhang Kaiming²^ORCID,Sanyal Mrinmoy¹,Tang Shaogeng¹,Weidenbacher Payton A.¹³,Li Shanshan²,Pham Tho D.⁴⁵,Pak John E.⁶,Chiu Wah²⁶⁷^ORCID,Kim Peter S.¹⁶^ORCID

Affiliation:

1. Department of Biochemistry & Stanford ChEM-H, Stanford University, Stanford, California 94305, United States

2. Department of Bioengineering & James H. Clark Center, Stanford University, Stanford, California 94305, United States

3. Department of Chemistry, Stanford University, Stanford, California 94305, United States

4. Department of Pathology, Stanford University, Stanford, California 94305, United States

5. Stanford Blood Center, Palo Alto, California 94304, United States

6. Chan Zuckerberg Biohub, San Francisco, California 94158, United States

7. Division of CryoEM and Bioimaging, SSRL, SLAC National Accelerator Laboratory, Menlo Park, California 94025, United States

Funder

Damon Runyon Cancer Research Foundation

NIH Office of the Director

National Institute of Allergy and Infectious Diseases

Ludwig Institute for Cancer Research

National Institute of General Medical Sciences

Chan Zuckerberg Biohub

Frank Quattrone and Denise Foderaro Family Research Fund

Maternal & Child Health Research Institute - Stanford Medicine

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acscentsci.0c01405

Reference87 articles.

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3. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

4. Convergent antibody responses to SARS-CoV-2 in convalescent individuals

5. Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

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