Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at μOR-Reference-Cited by-同舟云学术

Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at μOR

Published:2024-07-17 Issue:8 Volume:10 Page:1490-1503
ISSN:2374-7943
Container-title:ACS Central Science
language:en
Short-container-title:ACS Cent. Sci.

Author:

Ople Rohini S.¹²^ORCID,Ramos-Gonzalez Nokomis¹²^ORCID,Li Qiongyu³,Sobecks Briana L.⁴⁵⁶^ORCID,Aydin Deniz⁴⁵⁶^ORCID,Powers Alexander S.⁴⁵⁶,Faouzi Abdelfattah¹²^ORCID,Polacco Benjamin J.⁴⁵^ORCID,Bernhard Sarah M.¹²,Appourchaux Kevin¹²,Sribhashyam Sashrik¹²,Eans Shainnel O.⁷,Tsai Bowen A.⁷,Dror Ron O.⁴⁵⁶^ORCID,Varga Balazs R.¹²,Wang Haoqing⁶,Hüttenhain Ruth⁶,McLaughlin Jay P.⁷,Majumdar Susruta¹²^ORCID

Affiliation:

1. Center for Clinical Pharmacology, University of Health Sciences & Pharmacy at St. Louis and Washington University School of Medicine, St. Louis, Missouri 63110, United States

2. Department of Anesthesiology and Washington University Pain Center, Washington University School of Medicine, St. Louis, Missouri 63110, United States

3. Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California 94158, United States

4. Department of Computer Science, Stanford University, Stanford, California 94305, United States

5. Department of Structural Biology, Stanford University School of Medicine, Stanford, California 94305, United States

6. Department of Molecular & Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, United States

7. Department of Pharmacodynamics, University of Florida, Gainesville, Florida 032610, United States

Funder

Pharmaceutical Research and Manufacturers of America Foundation

National Institutes of Health

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acscentsci.4c00525

Reference63 articles.

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4. Parallel Synthesis of Hexahydrodiimidazodiazepines Heterocyclic Peptidomimetics and Their in Vitro and in Vivo Activities at μ (MOR), δ (DOR), and κ (KOR) Opioid Receptors

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