Spike Protein Mutation-Induced Changes in the Kinetic and Thermodynamic Behavior of Its Receptor Binding Domains Explain Their Higher Propensity to Attain Open States in SARS-CoV-2 Variants of Concern-Reference-Cited by-同舟云学术

Spike Protein Mutation-Induced Changes in the Kinetic and Thermodynamic Behavior of Its Receptor Binding Domains Explain Their Higher Propensity to Attain Open States in SARS-CoV-2 Variants of Concern

Published:2023-09-21 Issue:10 Volume:9 Page:1894-1904
ISSN:2374-7943
Container-title:ACS Central Science
language:en
Short-container-title:ACS Cent. Sci.

Author:

Singh Jasdeep¹^ORCID,Vashishtha Shubham²,Kundu Bishwajit²

Affiliation:

1. Department of Chemistry and Biochemistry, University of Denver, Denver, Colorado 80208, United States

2. Kusuma School of Biological Sciences, Indian Institute of Technology-Delhi, New Delhi 110016, India

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscentsci.3c00810

Reference47 articles.

1. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

2. SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development

3. Structural basis of receptor recognition by SARS-CoV-2

4. Cell entry mechanisms of SARS-CoV-2

5. Energetics of Spike Protein Opening of SARS-CoV-1 and SARS-CoV-2 and Its Variants of Concern: Implications in Host Receptor Scanning and Transmission

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