Peptide and Protein Cysteine Modification Enabled by Hydrosulfuration of Ynamide

Author:

Wang Changliu12,Zhao Zhenguang3,Ghadir Reem3,Yang Dechun4,Zhang Zhenjia1,Ding Zhe2,Cao Yuan5,Li Yuqing2,Fassler Rosi6,Reichmann Dana6ORCID,Zhang Yujie5,Zhao Yongli2,Liu Can1,Bi Xiaobao4ORCID,Metanis Norman7ORCID,Zhao Junfeng1ORCID

Affiliation:

1. Affiliated Cancer Hospital, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, Guangdong P. R. China

2. National Research Center for Carbohydrate Synthesis, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, Jiangxi P. R. China

3. Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel

4. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals & College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, Zhejiang P. R. China

5. Department of Process Development, BeiGene Guangzhou Biologics Manufacturing Co., Ltd., Guangzhou 510700, Guangdong P. R. China

6. The Alexander Silberman Institute of Life Science, @The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel

7. Institute of Chemistry, The Alexander Silberman Institute of Life Science, The Center for Nanoscience and Nanotechnology, Casali Center for Applied Chemistry, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel

Funder

Israel Science Foundation

Hebrew University of Jerusalem

China Scholarship Council

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

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