Rational Chemical Design of Molecular Glue Degraders-Reference-Cited by-同舟云学术

Rational Chemical Design of Molecular Glue Degraders

Published:2023-04-11 Issue:5 Volume:9 Page:915-926
ISSN:2374-7943
Container-title:ACS Central Science
language:en
Short-container-title:ACS Cent. Sci.

Author:

Toriki Ethan S.¹²³,Papatzimas James W.¹²³^ORCID,Nishikawa Kaila¹²³,Dovala Dustin²⁴,Frank Andreas O.²⁴^ORCID,Hesse Matthew J.²⁴,Dankova Daniela¹²³,Song Jae-Geun²⁴,Bruce-Smythe Megan²⁴,Struble Heidi²⁴,Garcia Francisco J.²⁵,Brittain Scott M.²⁵,Kile Andrew C.²⁴,McGregor Lynn M.²⁵^ORCID,McKenna Jeffrey M.²⁵,Tallarico John A.²⁵,Schirle Markus²⁵^ORCID,Nomura Daniel K.¹²³⁶^ORCID

Affiliation:

1. Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, United States

2. Novartis-Berkeley Translational Chemical Biology Institute, Berkeley, California 94720, United States

3. Innovative Genomics Institute, Berkeley, California 94704, United States

4. Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States

5. Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States

6. Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, United States

Funder

Division of Chemistry

National Cancer Institute

Natural Sciences and Engineering Research Council of Canada

Mark Foundation For Cancer Research

Novartis-Berkeley Translational Chemical Biology Institute

Novartis Institutes for BioMedical Research

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscentsci.2c01317

Reference40 articles.

1. Proteolysis targeting chimeras (PROTACs) come of age: entering the third decade of targeted protein degradation

2. Molecular recognition of ternary complexes: a new dimension in the structure-guided design of chemical degraders

3. The Rise of Molecular Glues

4. Small-Molecule Modulation of Protein Homeostasis

5. Development of targeted protein degradation therapeutics

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