Application of Melt Extrusion in the Development of a Physically and Chemically Stable High-Energy Amorphous Solid Dispersion of a Poorly Water-Soluble Drug-Reference-Cited by-同舟云学术

Application of Melt Extrusion in the Development of a Physically and Chemically Stable High-Energy Amorphous Solid Dispersion of a Poorly Water-Soluble Drug

Published:2008-10-07 Issue:6 Volume:5 Page:994-1002
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Lakshman Jay P.¹,Cao Yu¹,Kowalski James¹,Serajuddin Abu T. M.¹

Affiliation:

1. Pharmaceutical and Analytical Development Department, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey 07936, and Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John’s University, Queens, New York 11439

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp8001073

Reference16 articles.

1. Solid dispersion of poorly water‐soluble drugs: Early promises, subsequent problems, and recent breakthroughs

2. Yoshioka, S.; Stella, V. J.Stability of drugs and dosage forms;Kluwer Academic/Plenum Publishers:New York, 2000; pp139−150.

3. Role of Thermodynamic, Molecular, and Kinetic Factors in Crystallization from the Amorphous State

Cited by 190 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Thermal decomposition of active pharmaceutical substances and accuracy of the related kinetic predictions: The case of nifedipine;Thermochimica Acta;2024-08

2. Dissolution Mechanism of Pharmaceuticals and Formulations by Nonequilibrium Thermodynamic Modeling;Exploring Computational Pharmaceutics ‐ AI and Modeling in Pharma 4.0;2024-06-21

3. Supersaturable diacyl phospholipid dispersion for improving oral bioavailability of brick dust molecule: A case study of Aprepitant;European Journal of Pharmaceutics and Biopharmaceutics;2024-04

4. Formulation and evaluation of multicomponent inclusion complex of cyclosporine A;Journal of Inclusion Phenomena and Macrocyclic Chemistry;2024-03-28

5. Development of Preclinical Formulations for Toxicology Studies;A Comprehensive Guide to Toxicology in Nonclinical Drug Development;2024