One-Pot Synthesis of (S)-Baclofen via Aldol Condensation of Acetaldehyde with Diphenylprolinol Silyl Ether Mediated Asymmetric Michael Reaction as a Key Step
Author:
Affiliation:
1. Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki-Aza Aoba-ku, Sendai, Miyagi 980-8578, Japan
Funder
Ministry of Education, Culture, Sports, Science, and Technology
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.5b02839
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1. Combining pot, atom and step economy (PASE) in organic synthesis. Synthesis of tetrahydropyran-4-ones
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3. Pot Economy in the Synthesis of Prostaglandin A1and E1Methyl Esters
4. One‐Pot High‐Yielding Synthesis of the DPP4‐Selective Inhibitor ABT‐341 by a Four‐Component Coupling Mediated by a Diphenylprolinol Silyl Ether
5. High-Yielding Synthesis of the Anti-Influenza Neuramidase Inhibitor (−)-Oseltamivir by Three “One-Pot” Operations
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